Nonnucleotide Reverse‐Transcriptase Inhibitors and Treatment Interruption
نویسندگان
چکیده
منابع مشابه
Structured Treatment Interruption
4 In the context of this discussion, a subtle distinction is made between structured treatment interruption (STI) and structured intermittent treatment (SIT). STI has generally referred to 1 or more periods of interruption of potent antiretroviral therapy after a period of full viral suppression, with the principal goal being stimulation of HIV-1-specific immune responses that might subsequentl...
متن کاملRationale and Strategies for Treatment Interruption
“the advent of highly active antiretroviral therapy in the mid 1990s resulted in a dramatic increase in survival of hiv patients, especially among those with advanced disease,” Dr. Wafaa El-Sadr said in beginning her February 2006 prn lecture. Follow-up studies, she explained, demonstrated the durability of this effect, with decreasing hivassociated morbidity and mortality during the late 1990s...
متن کاملSuperiority of protease inhibitors over nonnucleoside reverse-transcriptase inhibitors when highly active antiretroviral therapy is resumed after treatment interruption.
Forty-five human immunodeficiency virus (HIV)-infected patients stopped taking treatment but resumed taking it thereafter. All 11 who resumed treatment with their prior protease inhibitor (PI)-based regimen reattained an undetectable virus load, whereas this occurred for only 15 (44%) of 34 patients who resumed nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based treatment (P<.001). Dist...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2008
ISSN: 1058-4838,1537-6591
DOI: 10.1086/593361